Healthy aging made possible

$101,000,000

Prize Purse

XPRIZE Healthspan is a 7-year, $101 million global competition to revolutionize the way we approach human aging.

Overview



XPRIZE Healthspan is made possible thanks to the generosity of Co-Title Sponsors Hevolution and SOLVE FSHD, and other individual sponsors. Learn more about our sponsors and partners.

Meet The Teams

2D Antiaging Proteins Laguna Hills, United States

Milestone 1 Eligible

5PAudio Krakow, Poland

Milestone 1 Eligible

A NEW DIMENSION San Jose, United States

Milestone 1 Eligible

ABATE Qr- Acupoint Biosensor Assess Treat Evaluate Grand Forks B.C., Canada

Milestone 1 Eligible

Abe Yoando Pharma Co Ltd Tokyo, Japan

Milestone 1 Eligible

ABV Products New York, United States

Milestone 1 Eligible

Accutar Cranbury, United States

Milestone 1 Eligible

AGE-GRACER Petaling Jaya, Malaysia

Milestone 1 Eligible

Ageless - Genome Restoration Collective (AGRC) ??????, Singapore

Milestone 1 Eligible

AgelessRx Ann Arbor, United States

Milestone 1 Eligible

Agemica Palo Alto, United States

Milestone 1 Eligible

Algen San Francisco, United States

Milestone 1 Eligible

Allen Gee, MD, PhD, FAAN Cody, United States

Milestone 1 Eligible

Alpha Rejuvenation Kurashiki, Japan

Milestone 1 Eligible

Altay Therapeutics Inc San Carlos, United States

Milestone 1 Eligible

Ambrosia Labs Amsterdam, Netherlands

Milestone 1 Eligible

ANI Biome San Francisco, United States

Milestone 1 Eligible

Aptah Bio San Carlos, United States

Milestone 1 Eligible

ASAGI Labs Karuizawa, Nagano, Japan

Milestone 1 Eligible

ASIRT Health Palo Alto, CA, United States

Milestone 1 Eligible

AutoHeal Bengaluru, India

Milestone 1 Eligible

AutoPhagyGO ???, Japan

Milestone 1 Eligible

Axxium Life Cape Canaveral, United States

Milestone 1 Eligible

bBHC Seoul, Korea, South

Milestone 1 Eligible

Beat-FSHD Los Angeles, United States

Milestone 1 Eligible

Beiwe Davis, United States

Milestone 1 Eligible

BioArmor Kuala Lumpur, Malaysia

Milestone 1 Eligible

BlueBird Longevity Geneve, Switzerland

Milestone 1 Eligible

BOOCS & Plasmalogen Fukuoka, Japan

Milestone 1 Eligible

BrightCore Tokyo, Japan

Milestone 1 Eligible

Buckeye team Akron, United States

Milestone 1 Eligible

Canadian Translational Geroscience Network Montreal, Canada

Milestone 1 Eligible

CHANGS ???, China

Milestone 1 Eligible

Circadian San Diego, United States

Milestone 1 Eligible

Columbia University New York, United States

Milestone 1 Eligible

Cura Therapeutics Montreal, Canada

Milestone 1 Eligible

Cyclarity Therapeutics Novato, United States

Milestone 1 Eligible

DeAging Singapore, Singapore

Milestone 1 Eligible

Deciduous Therapeutics San Francisco, United States

Milestone 1 Eligible

EFFEPHARM Shanghai, China

Milestone 1 Eligible

EGAceutical La Jolla California, United States

Milestone 1 Eligible

Emen4Sport Bilbao, Spain

Milestone 1 Eligible

Enterprise Walnut Creek, United States

Milestone 1 Eligible

EON project Nord de Palma District, Spain

Milestone 1 Eligible

Eos SENOLYTIX Surfside, United States

Milestone 1 Eligible

Epicrispr Biotechnologies South San Francisco, United States

Milestone 1 Eligible

EpiTransfer Oslo, Norway

Milestone 1 Eligible

ERAP trial group Stockholm, Sweden

Milestone 1 Eligible

Eureka30 London, United Kingdom

Milestone 1 Eligible

Exomed Mudgee, Australia

Milestone 1 Eligible

ExoNovaX Seoul, Korea, South

Milestone 1 Eligible

Extended Longevity Protocol Kula, United States

Milestone 1 Eligible

Forever Young Knoxville, United States

Milestone 1 Eligible

FuturVille-VulcanVille Vulcan, Canada

Milestone 1 Eligible

GI Innovation Seoul, Korea, South

Milestone 1 Eligible

Gladden Longevity Irving, United States

Milestone 1 Eligible

Global Health Span Extension-Consortium Basel, Switzerland

Milestone 1 Eligible

Goda Lab Bunkyo City, Japan

Milestone 1 Eligible

Gplife Healthcare Pvt Ltd Surat, India

Milestone 1 Eligible

Happyvity Quebec, Canada

Milestone 1 Eligible

Heal Like Me Natick, United States

Milestone 1 Eligible

Health Quest San Jose, United States

Milestone 1 Eligible

Healthy Longevity Clinic Prague, Czech Republic

Milestone 1 Eligible

Help patients with Alzheimer's disease ???, China

Milestone 1 Eligible

HONYA M Tainan, Taiwan

Milestone 1 Eligible

Hoskinson Health Gillette, United States

Milestone 1 Eligible

HumanGood Duarte, United States

Milestone 1 Eligible

Ilumirra Wilmington, United States

Milestone 1 Eligible

Immortalite Honolulu, United States

Milestone 1 Eligible

Inheritor of Huang's Legacy HangZhou, China

Milestone 1 Eligible

Initiate Age Reversal Auckland, New Zealand

Milestone 1 Eligible

Inner Science Gig Harbor, United States

Milestone 1 Eligible

Intervene Immune Los Angeles, United States

Milestone 1 Eligible

Japan Longevity Consortium Tokyo, Japan

Milestone 1 Eligible

JK-New Beijing, China

Milestone 1 Eligible

JoeKai ???, China

Milestone 1 Eligible

Keymed Biosciences CM383 chengdu, China

Milestone 1 Eligible

Kimera Labs Miami, United States

Milestone 1 Eligible

Klotho Longevity Mill Valley, United States

Milestone 1 Eligible

LIFE IS LONG Chiyoda-ku Tokyo, Japan

Milestone 1 Eligible

LiGHT team New York, United States

Milestone 1 Eligible

Lionheart Health Inc Irvine, United States

Milestone 1 Eligible

Livvon Longer Fort Lauderdale, United States

Milestone 1 Eligible

LogIN (Longevity Innovator) Sendai, Japan

Milestone 1 Eligible

London Longevity Clinic London, United Kingdom

Milestone 1 Eligible

Longeveron Inc Miami, United States

Milestone 1 Eligible

Longevity Extension & Aging Prevention Network Chicago, United States

Milestone 1 Eligible

Longevity Immunotherapy Irvine, United States

Milestone 1 Eligible

Longevity Ukraine Kyiv, Ukraine

Milestone 1 Eligible

Lono jaeyak ?????, Korea, South

Milestone 1 Eligible

Maharaj Institute Regenerative Foundation Boynton Beach, United States

Milestone 1 Eligible

Marcus STAMINA Team Boston, United States

Milestone 1 Eligible

Matter Bio New York, United States

Milestone 1 Eligible

Memory Air Dana Point, United States

Milestone 1 Eligible

Metformin for Healthspan Extension (MetHealthspan) New York, United States

Milestone 1 Eligible

MetroBiotech Worcester, United States

Milestone 1 Eligible

Minicircle Austin, United States

Milestone 1 Eligible

Minovia Tirat Carmel, Israel

Milestone 1 Eligible

Mito-tags Palo Alto, United States

Milestone 1 Eligible

Mitochondrial All-Stars Blacksburg, United States

Milestone 1 Eligible

Mitochondrial Bioenergetics and Ketone Utilization San Diego, United States

Milestone 1 Eligible

Modalis Therapeutics Waltham, United States

Milestone 1 Eligible

MyMenu Moonshot Melbourne Beach, United States

Milestone 1 Eligible

MyoProtect Bonn, Germany

Milestone 1 Eligible

Nano innovation Buenos Aires, Argentina

Milestone 1 Eligible

NeuExcell Suzhou, China

Milestone 1 Eligible

NEXQ Irvine, United States

Milestone 1 Eligible

Nishimura lab Tokyo, Japan, Japan

Milestone 1 Eligible

Nonconformity St. Louis, United States

Milestone 1 Eligible

NOVOS Labs New York, United States

Milestone 1 Eligible

NUS Academy for Healthy Longevity Singapore, Singapore

Milestone 1 Eligible

NYC-Vita New York, United States

Milestone 1 Eligible

Optistasis Pittsburgh, United States

Milestone 1 Eligible

oRx-20 Age Deceleration Consortium Cambridge, United Kingdom

Milestone 1 Eligible

Pacific Neuroscience Institute Santa Monica, United States

Milestone 1 Eligible

Parrots Washington, United States

Milestone 1 Eligible

Pentara Brain Stride Millcreek, United States

Milestone 1 Eligible

PrintBio Surfside, United States

Milestone 1 Eligible

Project Otto Hamilton, New Zealand

Milestone 1 Eligible

Project Serotonin San Francisco, United States

Milestone 1 Eligible

Prometheus Cell Team Shanghai, China

Milestone 1 Eligible

Propion San Francisco, United States

Milestone 1 Eligible

Qu Biologics - RESILIENCE team Burnaby, Canada

Milestone 1 Eligible

R42 Group Palo Alto, United States

Milestone 1 Eligible

Reboot Labs Malibu, United States

Milestone 1 Eligible

Regenelead Shanghai, China

Milestone 1 Eligible

Regenerative Bio Inc ???, China

Milestone 1 Eligible

Rejuvenate Bio San Diego, United States

Milestone 1 Eligible

Rejuvenation Biotech Shanghai, China

Milestone 1 Eligible

Rejuvenation Centre Pretoria, South Africa

Milestone 1 Eligible

Rejuvenation Science Institute Campinas, Brazil

Milestone 1 Eligible

Rejuvenation through Low Frequency Ultrasound Galveston, United States

Milestone 1 Eligible

Renewal Bio Rehovot, Israel

Milestone 1 Eligible

reOrigin Nanjing, China

Milestone 1 Eligible

RETRO-EPIGERNA Macau, China

Milestone 1 Eligible

RPRGAON-Progeria Busan, Korea, South

Milestone 1 Eligible

Sanjeevini Mumbai, India

Milestone 1 Eligible

SNPM - CHU Nice Nice, France

Milestone 1 Eligible

Space Seed Tokyo, Japan

Milestone 1 Eligible

Space-Aging Research Institute (SARI) Miami Beach, United States

Milestone 1 Eligible

StatePlusPlus New York, United States

Milestone 1 Eligible

SUMMITYLE Beijing, China

Milestone 1 Eligible

TAZ Inc Tokyo, Japan

Milestone 1 Eligible

Team Armatus Bio Columbus, United States

Milestone 1 Eligible

Team Everest Tempe, AZ, USA, United States

Milestone 1 Eligible

Team GlyNAC Houston, United States

Milestone 1 Eligible

Team Gravity Tokyo, Japan

Milestone 1 Eligible

Team Infinity New York, United States

Milestone 1 Eligible

Team Inflammasome Lehi, United States

Milestone 1 Eligible

Team NovaVita ???, China

Milestone 1 Eligible

Team Sialic Acid Fukuoka, Japan

Milestone 1 Eligible

Team Twilight Beverly, United States

Milestone 1 Eligible

Team XM ???, China

Milestone 1 Eligible

The Healthy Mind and Body St. Louis, United States

Milestone 1 Eligible

The Immortality Project New York, United States

Milestone 1 Eligible

Thrive Precision Health Chandler, United States

Milestone 1 Eligible

TIME TRAVELER AND CURREIO Taito, Tokyo, Japan

Milestone 1 Eligible

Timeline Lausanne, Switzerland

Milestone 1 Eligible

Tricision Healthy Aging Vaccine Beijing, China

Milestone 1 Eligible

University Hospital Institute (IHU) HealthAge Toulouse, France

Milestone 1 Eligible

Unlimited Bio Coxen Hole, Honduras

Milestone 1 Eligible

Virtuleap Lisbon, Portugal

Milestone 1 Eligible

VITA Barcelona, Spain

Milestone 1 Eligible

Voodo Greenvale, United States

Milestone 1 Eligible

Wello Vilnius, Lithuania

Milestone 1 Eligible

XI Optimal Genetics Chanhassen, United States

Milestone 1 Eligible

YOXLO Leiden, Netherlands

Milestone 1 Eligible

Alaska International Healthspan Fairbanks, United States

Alpha and Omega New York, United States

Amchi gendynamy company limited Chengdu, China

Astonishing Labs Los Angeles, United States

BenchMark-BrainRecovery Las Cruces, United States

BHI Therapeutic Sciences New York, United States

De-AD Montreal, Canada

ELENAE Berkeley, United States

imperio alquimista Bello, Colombia

Morris Biotech LLC Dallas, United States

Nextrin Van Wyck, United States

Quantum Optima Health Houston, United States

solsai Ben Arous, Tunisia

SynerGen7 Haisla, Canada

Team Canurta Mississauga, Canada

Tellastella Tokyo, Japan

Showing 183 teams
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MILESTONE 1 ELIGIBLE REGISTERED TEAM

BARRIER

Traditional medicine focuses on treating symptoms of injury, illness, or disease once they develop. This reactive system extends life, but doesn’t proactively improve health, leaving millions grappling with poor quality of life and related economic challenges in their later years.

BREAKTHROUGH

A proactive, accessible therapeutic that reduces the risk of chronic age-related diseases, increases human healthspan, and extends quality of life well into our later years.

IMPACT

If these trials are successful, we will prove that it is possible to improve health as we age. This prize will help us begin to create guidelines and new solutions for healthy aging.

Success would profoundly change our approach to aging and positively affect quality-of-life and healthcare costs. Working across all sectors, we can democratize health and create a future where aging is full of potential.


HOW TO WIN

The winning team of the $101M XPRIZE Healthspan must demonstrate that their therapeutic treatment restores muscle, cognitive, and immune function by a minimum of 10 years, with a goal of 20 years, in persons aged 50-80 years. The therapeutic treatment must take 1 year or less.

The winning team of the $10M FSHD Bonus Purse must demonstrate that their therapeutic solution substantially improves FSHD-relevant muscle outcomes based on: 1) fat infiltration in muscle via any imaging modality or change in a relevant FSHD biomarker, and 2) corresponding improvement of muscle function, compared with controls. The therapeutic treatment must take less than 1 year.


PRIZE CATEGORIES

The competition is operated across two tracks:

XPRIZE Healthspan is a 7-year, $101 million global competition to revolutionize the way we approach human aging. To tackle this problem, competing teams will develop and test therapeutics that restore muscle, cognitive, and immune function by a minimum of 10 years with a goal of 20 years, and extend healthy life.

Awarding of the Grand Prize is indexed to improvements in function relative to age-related declines expected over 10-years ($61M), 15-years ($71M), or 20-years ($81M). Two $10M Milestone Awards will be divided amongst advancing teams, totaling $20M in Milestone Awards.

Launched alongside the 7-year, $101 million XPRIZE Healthspan global competition, the $10M FSHD Bonus Prize challenges innovators across the globe to find novel solutions for FSHD. Competing teams in the FSHD Bonus Prize will develop and test therapeutics that demonstrate substantial improvement in muscle function through a therapeutic treatment lasting 1 year or less in persons with genetically confirmed FSHD.

An additional $10M is reserved for the FSHD Bonus Prize, which includes a $2M Milestone Award, and $8M awarded to the First Place team.

For more information, please refer to the Competition Guidelines.


HOW TO REGISTER

Public announcement of the competition was launched on November 29, 2023.  Interested teams were invited to pre-register by submitting an Intent to Compete form on the XPRIZE Prize Operations Platform (“POP”) competition portal.

On July 31, 2024, Primary Registration and Qualifying Submissions for the competition began. Teams must submit Qualifying Submissions for XPRIZE Healthspan and the FSHD Bonus Prize by December 20, 2024, for the Judges to review their eligibility for a Milestone 1 Award. For more information on Qualifying Submissions, please refer to the Resources section.


Get Involved

Stay up to date with the competition and join our mission to extend healthy life by subscribing to our newsletter, becoming a supporter, or competing on a team.


ENDPOINTS COMMITTEE

Prize Activity

Advisory Board